Gene of dependence on nicotine
نویسندگان
چکیده
منابع مشابه
Neurobiology of nicotine dependence
Nicotine is a psychoactive ingredient in tobacco that significantly contributes to the harmful tobacco smoking habit. Nicotine dependence is more prevalent than dependence on any other substance. Preclinical research in animal models of the various aspects of nicotine dependence suggests a critical role of glutamate, g-aminobutyric acid (GABA), cholinergic and dopamine neurotransmitter interact...
متن کاملCannabinoid receptor 1 gene association with nicotine dependence.
CONTEXT The endogenous cannabinoid system has been implicated in drug addiction in animal models. The cannabinoid receptor 1 (CNR1) gene is 1 of the 2 receptors expressed in the brain. It has been reported to be associated with alcoholism and multiple drug abuse and dependence. OBJECTIVE To test the hypothesis that the CNR1 gene is associated with nicotine dependence. DESIGN Genotype-phenot...
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(Manuscript submitted to the Journal of Biomedical Informatics special issue on " Semantic BioMed Mashups ") 1 An ontology-driven semantic mash-up of gene and biological pathway information: Application to the domain of nicotine dependence Abstract Objectives: This paper illustrates how Semantic Web technologies (especially RDF, OWL, and SPARQL) can support information integration and make it e...
متن کاملThe psychobiology of nicotine dependence
There is abundant evidence to show that nicotine is the principal addictive component of tobacco smoke. The results of laboratory studies have shown that nicotine has many of the behavioural and neurobiological properties of a drug of dependence. This article focuses on the evidence that nicotine has the rewarding and reinforcing properties typical of an addictive drug and that these properties...
متن کاملPharmacological Intervention of Nicotine Dependence
Nicotine dependence is a major cause of mortality and morbidity all over the world. Various medications have been tried to treat nicotine dependence including nicotine replacement therapy, bupropion, and varenicline. A newer venture to nicotine dependence treatment is a nicotine vaccine which is yet to get footsteps in common practice. The present review assimilates various pharmacotherapeutic ...
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ژورنال
عنوان ژورنال: Kontakt
سال: 2006
ISSN: 1212-4117,1804-7122
DOI: 10.32725/kont.2006.056